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In larger dosesfludrocortisone acetate inhibits endogenous adrenal cortical secretionthymic activityand pituitary corticotropin excretionpromotes the deposition of liver glycogenandunless protein intake is adequateinduces negative nitrogen balance.

There is an enhanced corticosteroid effect in patients with hypothyroidism and in those with cirrhosis.

Use in Children The recommended dose is one-half tablet0.05mgto one tablet0.1mgdailyMake sure you take the full course as prescribed by your doctorDo not suddenly stop taking Fludrocortisone acetate as this may make you ill.

Infants born of mothers who have received substantial doses of fludrocortisone acetate during pregnancy should be carefully observed for signs of hypoadrenalism.

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